In the UK chronic gastrointestinal symptoms after cancer therapies have a similar impact as IBD. However, in contrast to patients with IBD, most of these patients won’t see a gastroenterologist. In this month’s Gut Editor’s Choice the causes of these side effects of cancer treatment are discussed, as well as the benefits of investigation and treatment.

In this podcast Mairi McLean, senior clinical lecturer and consultant in gastroenterology at the University of Aberdeen talks to some key stakeholders in this issue:

Professor Sir Mike Richards, national clinical director for cancer and end of life care, Department of Health
Jane Maher, chief medical officer for McMillian Cancer Support
Jon Rhodes, professor of gastroenterology and president of the British Society of Gastroenterology
Jervoise Andeyev, consultant gastroenterologist in pelvic radiation disease at the Royal Marsden NHS Trust, London

See also:
Practice guidance on the management of acute and chronic gastrointestinal problems arising as a result of treatment for cancer

Mairi McLean, Gut education editor, talks to Professor Mark Hull, Leeds Institute of Molecular Medicine, about his research into the action of polyunsaturated fatty acids on the formation of neoplams.

See also:
Omega-3 polyunsaturated fatty acids for the treatment and prevention of colorectal cancer

Before the UK national bowel cancer screening programmes were implemented, a pilot was set-up in England to see if results from randomised controlled trials could be replicated in the general population. Gut has recently published findings from the third round of this.

Co-author David Weller, Centre for Population Health Sciences–General Practice, University of Edinburgh, UK, talks to Gut’s associate editor William Grady about effectiveness of screening, uptake and its link to ethnicity, and the potential of different methods.

See also:
Performance measures in three rounds of the English bowel cancer screening pilot

Herbert Tilg (Medizinische Universität Innsbruck and associate editor of Gut) talks to Elaine Holmes (Imperial College London) about her research published in Gut.

See also:
Metabolic Surgery Profoundly Influences Gut Microbial-Host Metabolic Crosstalk

Herbert Tilg (Medizinische Universität Innsbruck and associate editor of Gut) talks to Vincent Wong (The Chinese University of Hong Kong) about his paper published in gut looking at the high incidence of colorectal neoplasm in patient with non-alcoholic steatohepatitis.

See also:
High prevalence of colorectal neoplasm in patients with non-alcoholic steatohepatitis

In this podcast Dr Herbert Tilg (Medizinische Universität Innsbruck and associate editor of Gut) talks to Prof. Peter Mannon (Division of Gastroenterology and Hepatology, University of Alabama at Birmingham) about his paper; Suppression of inflammation in ulcerative colitis by interferon-β-1a is accompanied by inhibition of IL-13 production.

Read this article on the Gut website

In this podcast Dr Herbert Tilg (Medizinische Universität Innsbruck and associate editor of Gut) talks to prof. Chris Day (University of Newcastle Upon Tyne) about his article in Gut on evaluating fibrosis in fatty liver disease.

See also:
Simple non-invasive fibrosis scoring systems can reliably exclude advanced fibrosis in patients with non-alcoholic fatty liver disease

Guy Boeckxstaens (associate editor of gut) talks to QiQI Zhou and G.Nicholas Verne (Ohio State University) about ther paper; MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome

In this podcast Professor Alexander Gerbes (Klinikum of the University of Munich, Germany, and an associate editor of Gut) talks to Professir Franco Trevisani(Università di Bologna, Italy) about the results of his research into treatment of elderly patients for hepatocellular carcinoma.

See also:
Treatments for hepatocellular carcinoma in elderly patients are as effective as in younger patients

Dr Herbert Tilg (of Gut and the Medizinische Universität Innsbruck) talks to Dr Alexander Swidsinski (Charité - Universitätsmedizin Berlin) about his paper on bacterial composition in appendicitis.

Related Gut article: Acute appendicitis is characterized by local invasion with Fusobacterium  nucleatum/necrophorum.